| WR | Thomas, Michael | Carr, Austin | |||
| WR | Meredith, Cameron | Smith, Tre’quan | |||
| WR | Ginn, Ted | Lewis, Tommylee | |||
| LT | Armstead, Terron | Bushrod, Jerome | |||
| LG | Peat, Andrus | LeRibeus, Josh | |||
| C | Unger, Max | Clapp, Will | |||
| RG | Warford, Larry | ||||
| RT | Ramczyk, Ryan | Leonard, Rock | |||
| TE | Watson, Ben | Hill, Josh | Hoomanawanui, Michael | Dan Arnold | |
| QB | Brees, Drew | Savage, Tom | Hill, Taysom | ||
| RB | Ingram, Mark* | Kamara, Alvin | Scott, Boston | West, Terrance | Edmunds, Trey |
| FB | Line, Zach | ||||
| DE | Jordan, Cameron | Okafor, Alex | Kikaha, Hau’oli | ||
| DT | Rankins, Sheldon | Mondeaux, Henry | |||
| DT | Davison, Tyeler | Onyemata, David | |||
| DE | Davenport, Marcus | Hendrickson, Trey | |||
| SLB | Klein, AJ | ||||
| MLB | Davis, Demario | Te’o, Manti | |||
| WLB | Anzalone, Alex | Robertson, Craig | |||
| CB | Lattimore, Marshon | Robinson, Patrick | Jamerson, Natrell | ||
| SS | Bell, Vonn | Banjo, Chris | |||
| FS | Williams, Marcus | Coleman, Kurt | |||
| CB | Crawley, Ken | Williams, PJ | |||
| P | Mostead, Thomas | ||||
| K | Lutz, Wil | ||||
| LS | Wood, Zach | ||||
|
*Mark Ingram is suspended for 4 games
|